Filgrastim is used to treat neutropenia, a condition in which the body makes too few neutrophils. Filgrastim granulocyte colonystimulating factor gcsf is used to stimulate the production of white blood cells, which prevents infection in patients whose white blood cell count has diminished because of the effects of anticancer drugs. Filgrastim injection is used to treat neutropenia low white blood cells that is caused by cancer medicines. It is used to help your body make more white blood cells. Filgrastim is also approved to help move stem cells from the bone marrow to the bloodstream so that they can be collected, stored, and then given back to the patient in autologous stem cell. Easily combine multiple files into one pdf document. It is a synthetic manmade form of a substance that is naturally produced in your body called a colony stimulating factor. Effect of filgrastim in a severe leucopenia associated. The product is available in singleuse vials and prefilled syringes. Filgrastim definition of filgrastim by medical dictionary. Filgrastim is a nonglycosylated, 175 amino acid containing protein, which is produced recombinantly by e. Filgrastim neupogen is a manmade protein that is similar to the naturally occurring protein, granulocytecolony stimulating factor gcsf.
Gcsf is produced in the body by the immune system and stimulates the formation of one type of white blood cell, the neutrophil. Pegfilgrastim is administered to patients with certain kinds of cancer to accelerate recovery from chemotherapy induced neutropenia. After the administration of filgrastim, the anc level and oral temperature were measured and documented every six hours. Filgrastim may also be used for purposes not listed in this medication guide. Pegfilgrastim treatment can be used to stimulate bone marrow to produce more neutrophils to fight infection in patients undergoing chemotherapy. Filgrastim granulocyte colonystimulating factor gcsf is used to stimulate the production of white blood cells. Filgrastim can cause your spleen to become enlarged and it could rupture tear. Find out what health conditions may be a health risk when taken with filgrastim injection. Pegfilgrastim has a human halflife of 15 to 80 hours, much longer than the parent filgrastim 34 hours. It stimulates the growth of a type of white blood cells called neutrophil granulocytes, or neutrophils.
Pronunciation of filgrastim with 2 audio pronunciations, 6 translations and more for filgrastim. There are many options to minimize or prevent the side effects of filgrastim. Factor estimulante vomitos, diarrea, colonias apatia neutrofilos. This free online tool allows to combine multiple pdf or image files into a single pdf document. It is a synthetic manmade form of a substance that is naturally produced in your. Commonly reported side effects of filgrastim include. Filgrastim is also approved to help move stem cells from the bone marrow to the bloodstream so that they can be collected, stored, and then given back to the patient in autologous stem cell transplantation. Neupogen bayer amgen factor estimulante vomitos, diarrea, colonias apatia neutrofilos.
Controindicazioni modifica il farmaco e controindicato nei soggetti con ipersensibilita nota al principio attivo o ad uno qualsiasi degli eccipienti. Webmd provides common contraindications for filgrastim injection. The singleuse vials contain either 300 mcg or 480 mcg filgrastim at a fill volume of 1. Get emergency medical help if you have signs of an allergic reaction. Dec 26, 2019 commonly reported side effects of filgrastim include. Pegfilgrastim has a human halflife of 15 to 80 hours. Filgrastim is in a class of medications called colonystimulating factors.
White blood cells are important to help you fight off. By continuing to browse the site you are agreeing to our policy on the use of cookies. This was a prospective, open, phase iv clinical trial in patients receiving chemotherapy for histologically confirmed cancer, with an oral temperature of 38. Our pdf merger allows you to quickly combine multiple pdf files into one single pdf document, in just a few clicks. This protein is expressed by peripheral blood mononuclear cells as well as monocytes.
To view the entire topic, please sign in or purchase a subscription. Biological medicines must be prescribed and dispensed by brand name, see biological medicines and biosimilar medicines, under guidance on prescribing. Gcsf also mobilizes stem cells, prompting them to enter the. Filgrastim indicaciones, dosificacion, presentacion. Jan 01, 2017 filgrastim injection is used to treat neutropenia low white blood cells that is caused by cancer medicines. Filgrastim, sold under the brand name neupogen among others, is a medication used to treat low neutrophil count. Medicines containing the active ingredient filgrastim emc. Filgrastim was administered subcutaneously in a dose of 5 mcgkgday, 24 hours after administration of cytotoxic therapy, for up to two weeks or until the anc reaches 10,000 cellsmm 3. Filgrastim genetical recombination including followon biologicsbiosimilars see attachment b.
Filgrastim by injection national library of medicine. Pegfilgrastim is administered to patients with certain kinds of. Low neutrophil counts may occur with hivaids, following chemotherapy or radiation poisoning, or be of an unknown cause. Granulocyte colonystimulating factor filgrastim in. How to merge pdfs and combine pdf files adobe acrobat dc. Filgrastim is also approved to treat neutropenia that is not caused by cancer treatment. This webapp provides a simple way to merge pdf files. Mar 15, 2020 filgrastim is used to treat neutropenia, a lack of certain white blood cells caused by cancer, bone marrow transplant, receiving chemotherapy, or by other conditions. Filgrastim side effects will improve after therapy is complete.
Filgrastim injection neupogen is also used to increase the chance of survival in people who have been exposed to harmful amounts of radiation, which can cause severe and lifethreatening damage to your. Filgrastim injection neupogen is also used to increase the chance of survival in people who have been exposed to harmful amounts of radiation, which can cause severe and lifethreatening damage to your bone marrow. Filgrastim is a manmade version of a certain natural substance made in your body. Filgrastim works in the bone marrow, where new blood cells are made. Filgrastim side effects are often predictable in terms of their onset, duration, and severity. It regulates the production and release of functional neutrophils from bone marrow within 24 hours of administration. See below for a comprehensive list of adverse effects. It works by helping the body make more neutrophils. Neutropenia may be a longstanding condition in which the body does not make enough. Filgrastim puede administrarse por inyeccion sc o por infusion i. Filgrastim, lenograstim, nartograstim, pegfilgrastim.